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This is the theoretical basis for endogenously supplied gamma-glutamylcysteines ability to raise GSH levels, as being the product of the GCL enzyme, it can be taken up by cells intact, where it feeds directly into glutathione synthase to be converted to glutathione, effectively bypassing the dysfunctional GCL
As well as being a natural antioxidant and detoxifying agent, glutathione also protects the body via more complex mechanisms
REM sleep plays a critical role in mood regulation, memory consolidation, and behavioral neuroscience making its preservation a meaningful consideration for long-term brain health
doi: 10.1038/s41581-022-00601-z 70 SpinelliRBabootaRGoggSBeguinotFBlherMNerstedtAet al
The relative contribution of each system is different depending on the cell type, as discussed in the following section